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EC Number Crystallization (Commentary)
Show all pathways known for 1.14.13.154Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.154crystal structures of EryK in complex with the azole inhibitors ketoconazole and clotrimazole
Show all pathways known for 1.14.13.154Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.154different crystal forms are harvested from distinct crystallization conditions: two ligand-free forms, one substrate bound and two inhibitors-bound. All crystals belong either to the monoclinc P2(1)or to the orthorhombic P2(1)2(1)2(1) space groups, and exhibit diffraction limits ranging from 2.3 to 1.6 A
Show all pathways known for 1.14.13.154Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.154vapor diffusion at 21°C, three crystal forms of EryK are obtained in different crystallization conditions: with His tag (His6-EryK) in low salt conditions, without tag (EryK) in high salt, and in complex with its substrate erythromycin D (ErD-EryK)
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