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EC Number Crystallization (Commentary)
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.219DFR-NADP+-flavonol (myricetin and quercetin) complexes, at room temperature, by hanging-drop vapour diffusion method. Complex DFR-NADP+-myricetin belongs to space group P21 (unit-cell parameters a = 47.23, b = 177.96, c = 92.60 A, beta = 104.8°). Complex DFR-NADP+-quercetin belongs to space group P6122 (unit-cell parameters a = b = 174.94, c = 290.18 A)
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.219molecular docking of substrates. A phenol ring of dihydrokaempferol, a catechol ring of dihydroquercetin, and a pyrogallol ring of dihydromyricetin respectively have two, three, and four hydrogen bonds formed with side chains of residue Asn132
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.219molecular docking of substrates. The number of hydrogen bonds is one, two, and two for the corresponding phenol, catechol, and pyrogallol rings, respectively
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.219purified recombinant enzyme in complex with NADPH and dihydroquercetin, X-ray diffraction structure determination and analysis at 1.8 A resolution
Results 1 - 4 of 4