EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
3.1.4.39 | 0.0000061 |
- |
cyclohexanaminium hydrogen [[4-(decanoylamino)phenyl](fluoro)methyl]phosphonate |
pH and temperature not specified in the publication |
714443 |
3.1.4.39 | 0.000009 |
- |
cyclohexanaminium hydrogen [4-(tetradecanoylamino)benzyl]phosphonate |
pH and temperature not specified in the publication |
714443 |
3.1.4.39 | 0.00001 |
- |
PF8380 |
pH and temperature not specified in the publication |
729701 |
3.1.4.39 | 0.000018 |
- |
cyclohexanaminium hydrogen [4-(decanoylamino)benzyl]phosphonate |
pH and temperature not specified in the publication |
714443 |
3.1.4.39 | 0.000024 |
- |
cyclohexanaminium hydrogen [[4-(decanoylamino)phenyl](hydroxy)methyl]phosphonate |
pH and temperature not specified in the publication |
714443 |
3.1.4.39 | 0.0000242 |
- |
cyclohexanaminium hydrogen [[4-(decanoylamino)phenyl](hydroxy)methyl]phosphonate |
pH and temperature not specified in the publication |
714443 |
3.1.4.39 | 0.000072 |
- |
cyclohexanaminium hydrogen [[4-(decanoylamino)phenyl](fluoro)methyl]phosphonate |
pH and temperature not specified in the publication |
714443 |
3.1.4.39 | 0.0001 |
- |
1-acyl glycerol 3-phosphate |
CPF4 FRET assay (change of fluorescence intensity), inihibition involves both a reduction in vmax and an increase in km, binding affinity is 1000fold stronger than to 1-alkyl-sn-glycero-3-phosphoethanolamine and analogue substrates |
697490 |
3.1.4.39 | 0.00011 |
- |
lysophosphatidic acid |
- |
665628 |
3.1.4.39 | 0.0002 |
- |
2-amino-2-(2-(4-octylphenyl) ethyl)propan-1,3-diol |
substrate p-nitrophenyl thymidine 5-monophosphate, pH 8.0, 30 min of incubation at 37°C, measuring absorbance at 405 nm, twofold higher KI compared to inhibitor S1P |
697080 |