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EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Reference
2.7.4.8
0.08
-
MgATP2-
pH 7.7, 25ºC
642702
2.7.4.8
0.11
-
9-(6-phosphonohexyl)guanine
pH 7.5, 30ºC
642697
2.7.4.8
0.14
-
9-(6,6-difluoro-6-phosphonohexyl)guanine
pH 7.5, 30ºC, higher affinity than 9-(6-phosphonohexyl)guanine for guanylate kinases al pH values below 7.5
642697
2.7.4.8
0.148
-
dGMP
versus GMP
700079
2.7.4.8
0.16
-
MgATP2-
pH 7.7, 25ºC, Y78F mutant
642702
2.7.4.8
0.215
-
GDP
pH 7.5, 25ºC
642701
2.7.4.8
0.4
-
dGMP
versus ATP
700079
2.7.4.8
0.45
-
9-(2-hydroxyethoxymethyl)guanine 5'-monophosphate
pH 7.5, isoenzyme 4
642698
2.7.4.8
0.57
-
dGMP
pH 7.5
642685
2.7.4.8
0.63
-
GMP
pH 7.7, 25ºC, Y78F mutant
642702
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