EC Number |
Cofactor |
Reference |
---|
1.14.14.91 | cytochrome P450 |
- |
348379, 348381, 348382, 348383, 348385, 348386, 348389, 660303, 675635 |
1.14.14.91 | cytochrome P450 |
a heme-thiolate protein (P-450) |
743513 |
1.14.14.91 | cytochrome P450 |
activity is dependent on NADPH:cytochrome P-450 reductase |
348370 |
1.14.14.91 | cytochrome P450 |
cytochrome P450-dependent monooxygenase |
348390 |
1.14.14.91 | cytochrome P450 |
electrons are transferred from NADPH, the preferential electron donor of the system, to cytochrome P-450 via NADPH-cytochrome P-450 reductase |
348374 |
1.14.14.91 | cytochrome P450 |
involved in hydroxylation |
348373 |
1.14.14.91 | cytochrome P450 |
required |
348367 |
1.14.14.91 | NADH |
50% of the activity with NADPH |
660303 |
1.14.14.91 | NADH |
NADH alone can not supply the enzyme with electrons. NADH, 0.5 mM, results in 51% stimulation when NADPH is present at a saturating level, 0.5 mM |
348374 |
1.14.14.91 | NADH |
NADH has a synergistic effect on NADPH-supported hydroxylation, at both nonsaturating, 0.1 mM, and near-saturating, 1 mM, concentrations of NADPH |
348373 |