EC Number   |
Cofactor |
Reference |
|---|
   1.14.14.22 | FMNH2 |
- |
392304, 735524, 735525, 735527, 735585, 735798, 735826, 735833, 736146, 736522, 736530, 736655, 736855 |
| 1.14.14.22 | FMNH2 |
essentially required |
736529 |
| 1.14.14.22 | FMNH2 |
the reduced form of flavin serves as a substrate of DszA |
735584 |
| 1.14.14.22 | more |
NADH flavin reductase, essentially required |
736529 |
| 1.14.14.22 | more |
no direct activity with NAD(P)H |
735584 |
| 1.14.14.22 | more |
the flavin reductase, EC 1.5.1.36, from Rhodococcus erythropolis strain D-1 grown in a medium containing dibenzothiophene as the sole source of sulfur is essential for the reactions of the two monooxygenases DszC and DszA in vivo. The purified flavin reductase contains no chromogenic cofactors and has a molecular mass of 86 kDa and four identical 22-kDa subunits. The enzyme catalyzes NADH-dependent reduction of flavin mononucleotide, FMN. The flavin reductase does not catalyze reduction of any nitroaromatic compound |
392304 |
| 1.14.14.22 | more |
the purified TdsA absolutely requires an oxidoreductase for its activity, oxidoreductase TdsD is completely FMN-dependent, and FAD does not act as a cofactor. TsdD is active with NADH and NADPH to the same extent. TdsA exhibits no activity in the absence of TdsD |
736530 |
| 1.14.14.22 | NADH |
the enzyme does not directly react with NADH, but uses the activity of the FMN:NADH oxidoreductase, DszD |
736855 |
