EC Number |
Cofactor |
Reference |
---|
1.1.1.215 | cytochrome c |
bound by the 44 kDa subunit |
684567 |
1.1.1.215 | cytochrome c |
bound by the middle subunit |
685666 |
1.1.1.215 | FAD |
- |
700265, 760370 |
1.1.1.215 | FAD |
bound to the enzyme's large 65 kDA subunit |
684567 |
1.1.1.215 | FAD |
enzyme bound to the large subunit |
685666 |
1.1.1.215 | more |
no activity with NADH |
286275 |
1.1.1.215 | more |
the larger enzyme domain is responsible for binding the cofactor and contains a conserved [GXGXXG (X17) D] motif that is characteristic of the NAD(P)H/NAD(P)+-binding region. It consists of residues 103-287, forming a seven-stranded parallel beta-sheet flanked by seven alpha-helices |
742168 |
1.1.1.215 | NAD+ |
- |
741418 |
1.1.1.215 | NADH |
- |
721369, 741418, 742168 |
1.1.1.215 | NADP+ |
- |
286273, 286274, 286275, 286278, 684567, 685666, 695779, 739910, 740963 |