EC Number   |
Cofactor |
Reference |
|---|
    1.1.1.198 | more |
an N-terminal conserved Gly13-X-X-X-Gly17-X-Gly19 sequence motif is present in the NAD(H)-binding region |
739915 |
| 1.1.1.198 | more |
enzyme AaBDH is active in the presence of cofactor NADP+ or NAD+, NAD+ is the preferred cofactor |
740520 |
| 1.1.1.198 | more |
no cofactor: NADP+ |
724125, 726116 |
| 1.1.1.198 | NAD+ |
- |
286162, 286163, 724125, 726116, 740520, 760303, 760425, 760892, 761009, 762115, 762171, 762321 |
| 1.1.1.198 | NAD+ |
strong preference for NAD+ over NADP+ is observed. When cofactor NAD+ is replaced by NADP+, the catalytic rate of refolded BDH is reduced to below 5% compared to NAD+. NAD+ docking into the active site of the BDH homology model for binding domain and mode analysis |
739915 |
| 1.1.1.198 | NADP+ |
25% as efficient as NAD+ |
286163 |
| 1.1.1.198 | NADP+ |
65-85% as efficient as NAD+ |
286162 |
| 1.1.1.198 | NADP+ |
low activity |
740520 |
| 1.1.1.198 | NADP+ |
strong preference for NAD+ over NADP+ is observed. When cofactor NAD+ is replaced by NADP+, the catalytic rate of refolded BDH is reduced to below 5% compared to NAD+ |
739915 |
