EC Number |
Cofactor |
Reference |
---|
4.4.1.11 | pyridoxal 5'-phosphate |
4 mol per mol of enzyme |
34520, 34523, 34526 |
4.4.1.11 | pyridoxal 5'-phosphate |
increases the half-life of methoxypolyethylene glycol succinimidyl glutarate 5000 treated recombinant METase holoenzyme in a dose-dependent manner |
661424 |
4.4.1.11 | pyridoxal 5'-phosphate |
- |
34515, 34516, 34518, 34521, 34522, 34530, 34531, 34533, 34534, 34535, 649139, 649323, 649595, 650615, 650770, 651771, 653114, 660621, 660756, 661430, 677329, 680553, 682347, 690268, 691377, 691380, 691957, 692665, 694318, 701880, 714123, 728927, 729181, 729320, 729426, 748205, 748253, 749242 |
4.4.1.11 | pyridoxal 5'-phosphate |
absence of an aldimine bond between the active site Lys210 and pyridoxal 5'-phosphate in enzyme crystals, grown in monomethyl ether polyethylene glycol 2000 in the presence of ammonium sulfate |
714356 |
4.4.1.11 | pyridoxal 5'-phosphate |
4 mol of pyridoxal 5'-phosphate per mole of enzyme |
728952 |
4.4.1.11 | pyridoxal 5'-phosphate |
PLP-binding domain (residues 63-261) is typical for PLP-dependent enzymes with the type I fold |
746664 |
4.4.1.11 | pyridoxal 5'-phosphate |
protein-to-cofactor ratio is 2:1. The cofactor is removable by incubating with hydroxylamine hydrochloride and is readily restored by incubation with free PLP |
747532 |