EC Number |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
---|
3.4.24.87 | -999 |
- |
more |
kcat: 0.83 per min for FRETS-VWF73, a fluorescent synthetic peptide, corresponding to residues Asp1596-Arg1668 of von Willebrand factor domain A2 and containing the Tyr1605-Met1606 bond cleaved by ADAMTS13 |
669524 |
3.4.24.87 | 0.0019 |
- |
VWF115 |
pH 7.8, 37°C, recombinant wild-type enzyme |
711564 |
3.4.24.87 | 0.0062 |
- |
VWF115 |
pH 7.8, 37°C, recombinant mutant R349A |
711564 |
3.4.24.87 | 0.008 |
- |
VWF115 D1614A mutant |
pH 7.8, 37°C, recombinant wild-type enzyme |
711564 |
3.4.24.87 | 0.00875 |
- |
VWF115 D1614A mutant |
pH 7.8, 37°C, recombinant mutant R349A |
711564 |
3.4.24.87 | 0.14 |
- |
von Willebrand factor 115 |
recombinant enzyme, at 37°C |
669457 |
3.4.24.87 | 0.31 |
- |
FRET-VWF115 peptide |
pH 7.8, 37°C, recombinant mutant D187A |
711560 |
3.4.24.87 | 0.52 |
- |
von Willebrand factor 115 |
wild type enzyme, in 20 mM Tris-HCl (pH 7.8), 150 mM NaCl, 5 mM CaCl2, at 37°C |
719160 |
3.4.24.87 | 0.62 |
- |
VWF115 |
mutant R568K/F592Y/R660K/Y661F/Y665F, pH not specified in the publication, temperature not specified in the publication |
735183 |
3.4.24.87 | 0.67 |
- |
HRPH-A2-B |
- |
682523 |