EC Number   |
|---|
    1.3.1.70 | - |
| 1.3.1.70 | 14-SR, DNA and amino acid sequence determination and analysis, expression pattern, overview |
| 1.3.1.70 | a Neurospora crassa enzyme-deficient erg-3 mutant strain mat a and a yeast erg-4 mutant strain AP2 cannot be complemented by expression of 6 chimeric enzyme mutants variants constructed from the enzyme encoded by gene TM7SF2 and the Neurospora crassa gene erg-3 encoded enzyme |
| 1.3.1.70 | an enzyme-deficient erg-3 mutant strain mat a and a yeast erg-4 mutant strain AP2 cannot be complemented by expression of 6 chimeric enzyme mutants variants constructed from the enzyme encoded by erg-3 and the human gene TM7SF2 encoding the SR-1 protein |
| 1.3.1.70 | cDNA expression in COS-7 cells |
| 1.3.1.70 | DNA and amino acid sequence determination and analysis of 2 mutants, i.e. TM7SF2 and LBR, with autosomal recessive HEM/Greenberg skeletal dysplasia expressing a defective, truncated enzyme |
| 1.3.1.70 | expressed in Saccharomyces cerevisiae |
| 1.3.1.70 | expression of LBR in COS-1 cells |
| 1.3.1.70 | gene erg24, DNA and amino acid sequence determination, subcloning in Escherichia coli strain DH5alpha, complementation of the enzyme-deficient Saccharomyces cerevisiae erg24 mutant strain AP2 |
| 1.3.1.70 | gene TM7SF2, promoter analysis, the promoter contains a 5'-ATTGG-3' sequence, an inverted CCAAT-box, 14 bp upstream the -73/-64 SRE-like motif, and is a region responsible for promoter regulation by sterols and by coexpressed SREBP-2, expression analysis, overview |
