EC Number   |
|---|
    1.14.15.18 | cloning of several novel intron 2-containing, noncoding splice variant mRNAs for CYP27b1 in 1,25(OH)2D3-producing HKC-8 human proximal tubule and THP-1 monocytic cells. Noncoding splice variants of CYP27b1 are functionally active and may play a significant role in the regulation of 1,25(OH)2D3 synthesis during normal physiology |
| 1.14.15.18 | expressed in human kidney proximal tubular epithelial cell line HKC-8 |
| 1.14.15.18 | expression in COS cells, reconstituted with recombinant cytochrome P-450, recombinant adrenodoxin, and recombinant adrenodoxin reductase |
| 1.14.15.18 | expression in COS cells, vitamin D3 25- and 1alpha-hydroxylase, DNA sequence analysis |
| 1.14.15.18 | expression in Escherichia coli |
| 1.14.15.18 | expression in Escherichia coli JM109, coexpression of adrenodoxin and NADPH-adrenodoxin reductase for reconstitution of the system |
| 1.14.15.18 | expression in LLC-PK1-cells |
| 1.14.15.18 | expression of His-tagged CYP27B1 in Escherichia coli strain JM109 |
| 1.14.15.18 | expression of vitamin D hydroxylases in the VDR-/- mouse model, overview |
| 1.14.15.18 | expression of wild-type and mutant enzymes in Escherichia coli strain DH5alpha |
