EC Number   |
Subunits |
Reference |
|---|
    3.5.99.2 | ? |
x * 26840, sequence calculation |
718509 |
| 3.5.99.2 | ? |
x * 30000, SDS-PAGE |
-, 733301 |
| 3.5.99.2 | dimer |
overall dimeric organization in which N-terminal domains and C-terminal domains form ThiD-like and TenA-like local dimers, A relatively flexible linker region composed of a loop and a short helix joins the two domains, domain organization, overview |
718477 |
| 3.5.99.2 | dimer |
x-ray crystallography |
667651 |
| 3.5.99.2 | homotetramer |
4 * 24000, SDS-PAGE |
733003 |
| 3.5.99.2 | homotetramer |
4 * 25000, SDS-PAGE |
711977 |
| 3.5.99.2 | homotetramer |
4 * 25643, calculated from amino acid sequence |
711977 |
| 3.5.99.2 | monomer |
1 * 100000, SDS-PAGE |
246760 |
| 3.5.99.2 | More |
THI20 is a trifunctional enzyme containing an N-terminal HMP kinase/HMP-P kinase (ThiD-like) domain and a C-terminal thiaminase II (TenA-like) domain. The ThiD-like dimer observed in THI20 resembles other ThiD structures, the TenA-like domain, which is tetrameric in all previously reported structures, forms a dimer |
718477 |
| 3.5.99.2 | trimer |
in vitro |
713350 |
