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EC Number
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Commentary Substrates
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Commentary (Products)
Reversibility
6.5.1.2
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
NAD+-dependent DNA ligase LigN is non-essential for cell viability. Haloferax volcanii also encodes the ATP-dependent DNA ligase LigA. As with LigN, LigA is also non-essential for cell viability. Simultaneous inactivation of both proteins is lethal, however, indicating that they share an essential function
Haloferax volcanii
AMP + diphosphate + (deoxyribonucleotide)n+m
-
?
6.5.1.2
ATP + (dT)10
-
Thermus thermophilus
?
-
?
6.5.1.2
ATP + 5'-phosphate terminus of deoxyribonucleotides
-
Salmonella enterica subsp. enterica serovar Typhimurium
?
-
?
6.5.1.2
ATP + 5'-phosphate terminus of deoxyribonucleotides
-
Bacillus subtilis
?
-
?
6.5.1.2
ATP + 5'-phosphate terminus of deoxyribonucleotides
-
Thermus thermophilus
?
-
?
6.5.1.2
ATP + 5'-phosphate terminus of deoxyribonucleotides
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Escherichia coli
?
-
?
6.5.1.2
ATP + 5'-phosphoryl termini of poly(dA-dT)
-
Thermus thermophilus
?
-
?
6.5.1.2
ATP + acridinium-ester labelled DNA
-
Staphylococcus aureus
?
-
?
6.5.1.2
ATP + DNA
-
Melanoplus sanguinipes
?
-
?
6.5.1.2
ATP + nicked DNA
-
Escherichia coli
AMP + diphosphate + ?
-
?
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