EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.4.1.8 | 2 ATP + 4-acetylpyridine + HCO3- + H2O + H+ |
22% of the activity with acetophenone |
Aromatoleum aromaticum |
2 ADP + 2 phosphate + 2-oxo-3-(pyridin-4-yl)propanoate |
- |
? |
6.4.1.8 | 2 ATP + 4-acetylpyridine + HCO3- + H2O + H+ |
22% of the activity with acetophenone |
Aromatoleum aromaticum EbN1 |
2 ADP + 2 phosphate + 2-oxo-3-(pyridin-4-yl)propanoate |
- |
? |
6.4.1.8 | 2 ATP + acetophenone + HCO3- + H2O + H+ |
- |
Aromatoleum aromaticum |
2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate |
- |
? |
6.4.1.8 | 2 ATP + acetophenone + HCO3- + H2O + H+ |
anaerobic ethylbenzene metabolism in the betaproteobacterium Aromatoleum aromaticum is initiated by anaerobic oxidation to acetophenone via (S)-1-phenylethanol. The subsequent carboxylation of acetophenone to benzoylacetate is catalyzed by an acetophenone-induced enzyme |
Aromatoleum aromaticum |
2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate |
- |
? |
6.4.1.8 | 2 ATP + acetophenone + HCO3- + H2O + H+ |
the enzyme shows uncoupled ATPase activity with either bicarbonate or acetophenone in the absence of the second substrate. These observations indicate that both substrates may be phosphorylated. Purified enzyme shows no activity with GTP, CTP, UTP or ITP |
Aromatoleum aromaticum |
2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate |
- |
? |
6.4.1.8 | 2 ATP + acetophenone + HCO3- + H2O + H+ |
- |
Aromatoleum aromaticum EbN1 |
2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate |
- |
? |
6.4.1.8 | 2 ATP + acetophenone + HCO3- + H2O + H+ |
anaerobic ethylbenzene metabolism in the betaproteobacterium Aromatoleum aromaticum is initiated by anaerobic oxidation to acetophenone via (S)-1-phenylethanol. The subsequent carboxylation of acetophenone to benzoylacetate is catalyzed by an acetophenone-induced enzyme |
Aromatoleum aromaticum EbN1 |
2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate |
- |
? |
6.4.1.8 | 2 ATP + acetophenone + HCO3- + H2O + H+ |
the enzyme shows uncoupled ATPase activity with either bicarbonate or acetophenone in the absence of the second substrate. These observations indicate that both substrates may be phosphorylated. Purified enzyme shows no activity with GTP, CTP, UTP or ITP |
Aromatoleum aromaticum EbN1 |
2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate |
- |
? |
6.4.1.8 | 2 ATP + propiophenone + HCO3- + H2O + H+ |
108% of the activity with acetophenone |
Aromatoleum aromaticum |
2 ADP + 2 phosphate + 4-oxo-4-phenylbutanoate |
- |
? |
6.4.1.8 | 2 ATP + propiophenone + HCO3- + H2O + H+ |
108% of the activity with acetophenone |
Aromatoleum aromaticum EbN1 |
2 ADP + 2 phosphate + 4-oxo-4-phenylbutanoate |
- |
? |