EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.2.3.135 | (2E,6E)-farnesyl diphosphate |
- |
Omphalotus olearius |
DELTA6-protoilludene + diphosphate |
- |
? |
4.2.3.135 | (2E,6E)-farnesyl diphosphate |
- |
Stereum hirsutum |
DELTA6-protoilludene + diphosphate |
- |
? |
4.2.3.135 | (2E,6E)-farnesyl diphosphate |
- |
Postia placenta |
DELTA6-protoilludene + diphosphate |
- |
? |
4.2.3.135 | (2E,6E)-farnesyl diphosphate |
- |
Omphalotus olearius |
DELTA6-protoilludene + diphosphate |
single product |
? |
4.2.3.135 | (2E,6E)-farnesyl diphosphate |
- |
Stereum hirsutum |
DELTA6-protoilludene + diphosphate |
main product for isoforms 25180, 64702, 73029. Isoforms 64702 and 73029 appear to be less specific than other previously described DELTA6-protoilludene synthases, and are capable of simultaneously producing a 1,10-cyclization-derived scaffold, beta-elemene, when expressed in a heterologous host |
? |
4.2.3.135 | (2E,6E)farnesyl diphosphate |
- |
Armillaria gallica |
6-protoilludene + diphosphate |
- |
? |
4.2.3.135 | more |
in the presence of Ca2+, DELTA6-protoilludene synthases catalyze diverse cyclization reactions. DELTA6-Protoilludene and (E)-beta-caryophyllene result from a 1,11 cyclization of (2E,6E)-farnesyl diphosphate following metal ion mediated ionization. The intermediate trans-humulyl cation may undergo a hydride shift followed by two cyclizations and a deprotonation to yield DELTA6-protoilludene. Diphosphate enzyme-coupled spectrophotometric assay |
Stereum hirsutum |
? |
- |
? |
4.2.3.135 | more |
in the presence of Ca2+, DELTA6-protoilludene synthases catalyze diverse cyclization reactions. DELTA6-Protoilludene and (E)-beta-caryophyllene result from a 1,11 cyclization of (2E,6E)-FPP following metal ion mediated ionization. The intermediate trans-humulyl cation may undergo a hydride shift followed by two cyclizations and a deprotonation to yield DELTA6-protoilludene. Diphosphate enzyme-coupled spectrophotometric assay |
Omphalotus olearius |
? |
- |
? |
4.2.3.135 | more |
in the presence of Ca2+, DELTA6-protoilludene synthases catalyze diverse cyclization reactions. DELTA6-Protoilludene and (E)-beta-caryophyllene result from a 1,11-cyclization of (2E,6E)-farnesyl diphosphate following metal ion mediated ionization. The intermediate trans-humulyl cation may undergo a hydride shift followed by two cyclizations and a deprotonation to yield DELTA6-protoilludene Diphosphate enzyme-coupled spectrophotometric assay |
Stereum hirsutum |
? |
- |
? |
4.2.3.135 | more |
PpSTS-08 product formation is identified by GC-MS and NMR analysis |
Postia placenta |
? |
- |
? |