EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.2.1.114 | (1E)-hex-1-ene-1,2,6-tricarboxylic acid + H2O |
- |
Methanocaldococcus jannaschii |
(2R)-hexane-1,2,6-tricarboxyclic acid |
- |
? |
4.2.1.114 | (1E)-pent-1-ene-1,2,5-tricarboxylic acid + H2O |
- |
Methanocaldococcus jannaschii |
(2R)-pentane-1,2,5-tricarboxylic acid |
- |
? |
4.2.1.114 | (2R)-butane-1,2,4-tricarboxylic acid |
- |
Methanocaldococcus jannaschii |
but-1-ene-1,2,4-tricarboxylic acid + H2O |
- |
? |
4.2.1.114 | (R)-2-hydroxybutane-1,2,4-tricarboxylate |
i.e. (R)-homocitrate, overall reaction, the enzyme catalyzes both the dehydration of (R)-homocitrate to form cis-homoaconitate, and hydration producing homoisocitrate |
Methanocaldococcus jannaschii |
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate |
i.e. homoisocitrate |
r |
4.2.1.114 | (R)-2-hydroxybutane-1,2,4-tricarboxylate |
- |
Cryptococcus neoformans var. grubii serotype A |
(Z)-but-1-ene-1,2,4-tricarboxylate + H2O |
- |
? |
4.2.1.114 | (R)-2-hydroxybutane-1,2,4-tricarboxylate |
i.e. (R)-homocitrate, first half-reaction |
Methanocaldococcus jannaschii |
(Z)-but-1-ene-1,2,4-tricarboxylate + H2O |
i.e. cis-homoaconitate, the activity in the reverse direction is similar as with (R)-homocitrate |
r |
4.2.1.114 | (R)-2-hydroxybutane-1,2,4-tricarboxylate |
- |
Cryptococcus neoformans var. grubii serotype A H99 / ATCC 208821 / CBS 10515 / FGSC 9487 |
(Z)-but-1-ene-1,2,4-tricarboxylate + H2O |
- |
? |
4.2.1.114 | (R)-2-hydroxybutane-1,2,4-tricarboxylate + H2O |
- |
Cryptococcus neoformans var. grubii serotype A |
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate |
- |
? |
4.2.1.114 | (R)-2-hydroxybutane-1,2,4-tricarboxylate + H2O |
- |
Cryptococcus neoformans var. grubii serotype A H99 / ATCC 208821 / CBS 10515 / FGSC 9487 |
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate |
- |
? |
4.2.1.114 | (Z)-but-1-ene-1,2,4-tricarboxylate + H2O |
- |
Cryptococcus neoformans var. grubii serotype A |
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate |
- |
? |