EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
  4.1.2.46 | (2R)-2-hydroxy-2-methylbutanenitrile |
- |
Linum usitatissimum |
cyanide + 2-butanone |
- |
? |
| 4.1.2.46 | (R)-2-butanone-cyanhydrin |
- |
Linum usitatissimum |
HCN + butanone |
- |
? |
| 4.1.2.46 | 2-hydroxy-2-methylpropanenitrile |
i.e. acetone cyanohydrin |
Linum usitatissimum |
cyanide + acetone |
- |
? |
| 4.1.2.46 | 2-hydroxy-2-methylpropanenitrile |
the enzyme is involved in the catabolism of cyanogenic glycosides in young seedlings of Linum usitatissimum |
Linum usitatissimum |
cyanide + acetone |
- |
? |
| 4.1.2.46 | 3,3-dimethyl-2-butanone + acetone cyanohydrin |
- |
Prunus persica |
2-hydroxy-2,3,3-trimethylbutanenitrile + acetone |
- |
? |
| 4.1.2.46 | acetyltrimethylsilane + acetone cyanohydrin |
- |
Prunus persica |
(R)-2-trimethylsilyl-2-hydroxy-ethylcyanide + acetone |
enantioselective transcyanation. Under optimum conditions, both acetyltrimethylsilane conversion to (R)-2-trimethylsilyl-2-hydroxy-ethylcyanide and enantiomeric excess of the product are above 99%. The silicon atom in acetyltrimethylsilane has a great effect on the eaction and both the substrate conversion and the product enantiomeric excess are much higher than those in its carbon counterpart 3,3-dimethyl-2-butanone |
? |
| 4.1.2.46 | cyanide + 2-methylcyclopentanone |
- |
Linum usitatissimum |
? |
- |
? |
| 4.1.2.46 | cyanide + 2-pentanone |
93% enantiomeric excess |
Linum usitatissimum |
(2R)-2-hydroxy-2-methylpentanenitrile |
- |
? |
| 4.1.2.46 | cyanide + acetone |
- |
Linum usitatissimum |
2-hydroxy-2-methylpropanenitrile |
- |
? |
| 4.1.2.46 | cyanide + acetone |
natural substrates for the (R)-oxynitrilase from Linum usitatissimum are acetone and butan-2-one, which are the building blocks of the cyanogenic glycosides in Linum, linamarin and lotaustralin, or linustatin and neolinustatin, respectively |
Linum usitatissimum |
2-hydroxy-2-methylpropanenitrile |
- |
? |
