EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    3.5.4.25 | 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-triphosphate + H2O |
- |
Bacillus subtilis |
? |
- |
? |
| 3.5.4.25 | 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-triphosphate + H2O |
- |
Escherichia coli |
? |
- |
? |
| 3.5.4.25 | 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone triphosphate + 2 H2O |
compound does serve as a substrate but not as kinetically competent intermediate |
Escherichia coli |
formate + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate + diphosphate |
- |
? |
| 3.5.4.25 | 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone triphosphate + 2 H2O |
formamide-type intermediate analogue |
Escherichia coli |
formate + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate + diphosphate |
- |
? |
| 3.5.4.25 | 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone triphosphate + H2O |
formamide-type intermediate analogue |
Escherichia coli |
2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate + diphosphate |
- |
? |
| 3.5.4.25 | 8-oxo-dGTP + H2O |
- |
Escherichia coli |
? |
- |
? |
| 3.5.4.25 | dGTP + H2O |
- |
Escherichia coli |
formate + 2,5-diamino-6-hydroxy-4-(5-phospho-deoxyribosylamino)pyrimidine + diphosphate |
- |
? |
| 3.5.4.25 | GTP + 3 H2O |
- |
Escherichia coli |
formate + 2,5-diamino-6-beta-ribosylamino-4(3H)-pyrimidinone 5'-phosphate + diphosphate |
spontaneous isomerization into the alpha-isomer, also the product can easily spontaneously decompose under formation of 2,4,5-triamino-4-(3H)-pyrimidone |
? |
| 3.5.4.25 | GTP + 3 H2O |
first committed step in the biosynthesis of riboflavin, overview |
Escherichia coli |
formate + 2,5-diamino-6-beta-ribosylamino-4(3H)-pyrimidinone 5'-phosphate + diphosphate |
- |
? |
| 3.5.4.25 | GTP + 3 H2O |
- |
Helicobacter pylori |
formate + 2,5-diamino-6-hydroxy-4-(5-phospho-D-ribosylamino)pyrimidine + diphosphate |
- |
? |
