EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.4.22.38 | 2-aminobenzoyl-Gly-Pro-Hyp-Gly-Phe(NO2)-Gly-OH + H2O |
- |
Rattus norvegicus |
? |
- |
? |
| 3.4.22.38 | 2-aminobenzoyl-RPPGFSPFR-(3-nitrotyrosine) + H2O |
- |
Mus musculus |
? |
- |
? |
| 3.4.22.38 | Abz-His-Pro-Gly-Gly-Pro-Gln-EDDnp + H2O |
cathepsin k is unusual among the cysteine cathepsins since it can cleave substrates with Pro in the P2 position. A specific peptide substrate for cathepsin K is developed (kcat/Km: 426000/Msec) that is resistant to proteolysis by cathepsin B, L, S, F, H,V and the serine proteases (cathepsin G, chymotrypsin and leukocyte elastase) |
Homo sapiens |
? |
- |
? |
| 3.4.22.38 | Abz-HPGGPQ-EDDnp + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.22.38 | Ac-Lys-His-Pro-Lys-7-amido-3-carbamoylmethyl-4-methylcoumarin + H2O |
assay at pH 5.5, 37°C |
Homo sapiens |
Ac-Lys-His-Pro-Lys + 7-amino-3-carbamoylmethyl-4-methylcoumarin |
- |
? |
| 3.4.22.38 | Acetyl-Phe-Arg 4-methylcoumarin 7-amide + H2O |
- |
Homo sapiens |
Acetyl-Phe-Arg + 7-amino-4-methylcoumarin |
- |
? |
| 3.4.22.38 | aggrecan + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.22.38 | aggrecan + H2O |
degradation |
Canis lupus familiaris |
? |
- |
? |
| 3.4.22.38 | Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O |
31.29% activity compared to benzyloxycarbonyl-Gly-L-Pro-L-Arg-7-amido-4-methylcoumarin |
Paralichthys olivaceus |
Ala-Ala-Phe + 7-amino-4-methylcoumarin |
- |
? |
| 3.4.22.38 | alpha-isomerized C-telopeptide + H2O |
- |
Homo sapiens |
? |
- |
? |
