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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.4.21.60
benzoyl-Ile-Glu-Gly-Arg 4-nitroanilide + H2O
-
Oxyuranus scutellatus
benzoyl-Ile-Glu-Gly-Arg + 4-nitroaniline
-
?
3.4.21.60
Factor Xa-specific substrates + H2O
-
Oxyuranus scutellatus
?
-
?
3.4.21.60
Meizothrombin + H2O
des fragment 1
Oxyuranus scutellatus
?
-
?
3.4.21.60
more
no hydrolysis of: benzoyl-Phe-Arg 4-nitroanilide, D-Val-Leu-Lys 4-nitroanilide
Oxyuranus scutellatus
?
-
?
3.4.21.60
more
amidolytic activity
Oxyuranus scutellatus
?
-
?
3.4.21.60
more
enzyme acts on cell survival, regulating the expression of molecules as NO and avoiding cell death. Enzyme triggers release of interleukin 8, inhibits platelet activation and chemotaxis and causes uncoagulable blood by fibrinogen depletion
Lonomia obliqua
?
-
?
3.4.21.60
more
the enzyme does not show fibrinogen-clotting, platelet-aggregating, fibrinogenolytic and factor X activating activities. Very low amidolytic activity as detected by the hydrolysis of the chromogenic substrates D-Phe-Pip-Arg-4-naphthyl amide and D-Val-Leu-Lys-4-naphthylamide
Bothrops cotiara
?
-
?
3.4.21.60
Prethrombin 1 + H2O
-
Oxyuranus scutellatus
?
-
?
3.4.21.60
Prethrombin 2 + H2O
-
Oxyuranus scutellatus
?
-
?
3.4.21.60
prethrombin-1 + H2O
-
Oxyuranus scutellatus
?
-
?
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