EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.4.17.17 | alpha-tubulin + H2O |
- |
Homo sapiens |
detyrosinated tubulin + Tyr |
- |
? |
| 3.4.17.17 | alpha-tubulin + H2O |
the enzyme could be part of the mechanism that regulates the tyrosination state of microtubules |
Cricetulus griseus |
detyrosinated tubulin + Tyr |
- |
? |
| 3.4.17.17 | alpha-tubulin + H2O |
carboxy-terminal tyrosine of alpha-tubulin is removed by TCP and readded by tubulin tyrosine ligase (TTL) |
Homo sapiens |
detyrosinated tubulin + Tyr |
- |
? |
| 3.4.17.17 | alpha-tubulin + H2O |
MAP1B regulates tyrosination of alpha-tubulin in neuronal microtubules |
Mus musculus |
detyrosinated tubulin + Tyr |
- |
? |
| 3.4.17.17 | more |
may have the ability to remove C-terminal Tyr residues from proteins based on both its substrate binding pocket and the loops surrounding the active site pocket. Has enzymatic activity toward small peptides that contain C-terminal hydrophobic groups |
Caenorhabditis elegans |
? |
- |
? |
| 3.4.17.17 | tyrosinated tubulin + H2O |
- |
Gallus gallus |
tubulin + Tyr |
- |
? |
| 3.4.17.17 | tyrosinated tubulin + H2O |
- |
Cricetulus griseus |
tubulin + Tyr |
- |
? |
| 3.4.17.17 | tyrosinated tubulin + H2O |
- |
Mus musculus |
tubulin + Tyr |
- |
? |
| 3.4.17.17 | tyrosinated tubulin + H2O |
- |
Rattus norvegicus |
tubulin + Tyr |
- |
? |
| 3.4.17.17 | tyrosinated tubulin + H2O |
- |
Bos taurus |
tubulin + Tyr |
- |
? |
