EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.2.2.31 | DNA containing a 5-hydroxyuracil/adenine mismatch + H2O |
the enzyme has a moderate affinity for DNA containing a 5-hydroxyuracil/adenine mismatch |
Escherichia coli |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
- |
Escherichia coli |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
- |
Homo sapiens |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
- |
Schizosaccharomyces pombe |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
- |
Helicobacter pylori |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
- |
Corynebacterium pseudotuberculosis |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
- |
Rattus norvegicus |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
- |
Geobacillus stearothermophilus |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
highest activity |
Escherichia coli |
? |
- |
? |
3.2.2.31 | DNA containing a 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine mismatch + H2O |
the enzyme shows 6fold faster adenine removal compared to DNA containing a guanine:adenine mismatch. However, under conditions where the concentration of the enzyme is much lower than the concentration of DNA, 7,8-dihydro-8-oxo-2'-deoxyguanosine:adenine substrates are not quantitatively converted to product due to the inefficient turnover resulting from slow product release |
Escherichia coli |
? |
- |
? |