EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.1.8.2 | (R)-cyclosarin + H2O |
- |
Loligo vulgaris |
? |
- |
? |
| 3.1.8.2 | (R)-sarin + H2O |
- |
Loligo vulgaris |
? |
- |
? |
| 3.1.8.2 | (RS)-propan-2-yl methylphosphonofluoridate + H2O |
i.e. sarin |
Loligo vulgaris |
isopropyl phosphate methylphosphonate + fluoride |
- |
? |
| 3.1.8.2 | (RS)-propan-2-yl methylphosphonofluoridate + H2O |
i.e. sarin |
Sphingobium fuliginis |
isopropyl phosphate methylphosphonate + fluoride |
- |
? |
| 3.1.8.2 | (RS)-propan-2-yl methylphosphonofluoridate + H2O |
i.e. sarin |
Brevundimonas diminuta |
propan-2-yl methylphosphonate + fluoride |
- |
? |
| 3.1.8.2 | (S)-cyclosarin + H2O |
- |
Loligo vulgaris |
? |
- |
? |
| 3.1.8.2 | (S)-sarin + H2O |
- |
Loligo vulgaris |
? |
- |
? |
| 3.1.8.2 | (S)-sarin + H2O |
- |
Loligo vulgaris |
? |
the calculated free energy barrier for hydrolysis of (S)-sarin by the mechanism for diiisopropyl fluorophosphate is highly unfavorable. Hydrolysis of (S)-sarin proceeds by a mechanism in which Asp229 could activate an intervening water molecule for nucleophilic attack on the substrate |
? |
| 3.1.8.2 | 1,2,2-trimethylpropyl methylphosphonofluoridoate + H2O |
- |
Loligo vulgaris |
1,2,2-trimethylpropyl methylphosphonate + fluoride + H+ |
- |
? |
| 3.1.8.2 | 1-methylethyl methylphosphonofluoridoate + H2O |
- |
Loligo vulgaris |
1-methylethyl methylphosphonate + fluoride + H+ |
- |
? |
