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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
2.7.7.6
2'-C-methyl-ATP + RNAn
misincorporation frequency of approximately 1 in 7800 2'-C-methyl-ATP
Homo sapiens
diphosphate + RNAn+1
-
?
2.7.7.6
2'-deoxy-ATP + RNAn
misincorporation
Homo sapiens
diphosphate + RNAn+1
-
?
2.7.7.6
3'-deoxy-ATP + RNAn
misincorporation frequency of approximately 1 in 5 3'-dATP
Homo sapiens
diphosphate + RNAn+1
-
?
2.7.7.6
ATP + RNAn
-
Thermus thermophilus
diphosphate + RNAn+1
-
?
2.7.7.6
ATP + RNAn
-
Homo sapiens
diphosphate + RNAn+1
-
?
2.7.7.6
ATP + RNAn
-
Saccharomyces cerevisiae
diphosphate + RNAn+1
-
?
2.7.7.6
ATP + RNAn
-
Escherichia phage T7
diphosphate + RNAn+1
-
?
2.7.7.6
ATP + RNAn
the primer can be extended only in the presence of ATP. The length of the double-stranded region of RNA/DNA duplexes is important for the primer extension. The length of the double-stranded region of RNA/DNA duplexes is important for the primer extension performed by the enzyme. Under these in vitro conditions POLRMT has a preference for P/T duplexes with short hybridization regions
Homo sapiens
diphosphate + RNAn+1
-
?
2.7.7.6
CTP + RNAn
-
Thermus thermophilus
diphosphate + RNAn+1
-
?
2.7.7.6
CTP + RNAn
-
Saccharomyces cerevisiae
diphosphate + RNAn+1
-
?
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