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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81(2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate Aeropyrum pernix does not possess geranylgeranyl diphosphate synthase and has only C25-C25 ether lipids, but no C20-containing ether lipids. Aeropyrum pernix farnesylgeranyl diphosphate synthase is important in the biosynthesis of the hydrocarbon moiety of membrane lipids Aeropyrum pernix (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate - ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81(2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate farnesyl diphosphate is the allylic substrate with the highest activity Aeropyrum pernix (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate - ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81(2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate farnesyl diphosphate shows 93% of the activity with geranylgeranyl diphosphate. Stereochemistry of farnesylgeranyl diphosphate synthesized by FGPP synthase is unclear, but may be an all-E isomer because the same isomer is produced when dimethylallyl diphosphate, geranyl diphosphate, and (all-E)-farnesyl diphosphate, as well as (all-E)-geranylgeranyl diphosphate, are used as substrates. The stereochemistry of the C25 moiety of C20,C25-diether lipids is identical with that of the C20 moiety Natronomonas pharaonis (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate - ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81dimethylallyl diphosphate + 4 isopentenyl diphosphate dimethylallyl diphosphate shows 28% of the activity with farnesyl diphosphate Aeropyrum pernix (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate large amounts of intermediates are formed: geranyl diphosphate, farnesyl diphosphate, geranylgeranyl diphosphate ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81dimethylallyl diphosphate + 4 isopentenyl diphosphate dimethylallyl diphosphate shows 51% of the activity with farnesyl diphosphate. Stereochemistry of farnesylgeranyl diphosphate synthesized by FGPP synthase is unclear, but may be an all-E isomer because the same isomer is produced when dimethylallyl diphosphate, geranyl diphosphate, and (all-E)-farnesyl diphosphate, as well as (all-E)-geranylgeranyl diphosphate, are used as substrates. The stereochemistry of the C25 moiety of C20,C25-diether lipids is identical with that of the C20 moiety Natronomonas pharaonis (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate large amounts of intermediates are formed: geranyl diphosphate, farnesyl diphosphate, geranylgeranyl diphosphate ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81farnesyl diphosphate + 2 isopentenyl diphosphate biosynthesis of the polyprenyl side-chain of methanophenazine, an electron carrier utilized for methanogenesis Methanosarcina mazei (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate - ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81farnesyl diphosphate + 2 isopentenyl diphosphate the enzyme prefers geranylgeranyl diphosphate and farnesyl diphosphate as allylic substrate Methanosarcina mazei (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate (2E,6E,10E,14E)-geranylfarnesyl diphosphate is the main product, a considerable amount of geranylgeranyl diphosphate as an intermediate is also observed ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81geranyl diphosphate + 3 isopentenyl diphosphate slight activity Methanosarcina mazei (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate - ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81geranyl diphosphate + 3 isopentenyl diphosphate geranyl diphosphate shows 72% of the activity with farnesyl diphosphate Aeropyrum pernix (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate - ?
Show all pathways known for 2.5.1.81Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.81geranyl diphosphate + 3 isopentenyl diphosphate geranyl diphosphate shows 81% of the activity with farnesyl diphosphate. Stereochemistry of farnesylgeranyl diphosphate synthesized by FGPP synthase is unclear, but may be an all-E isomer because the same isomer is produced when dimethylallyl diphosphate, geranyl diphosphate, and (all-E)-farnesyl diphosphate, as well as (all-E)-geranylgeranyl diphosphate, are used as substrates. The stereochemistry of the C25 moiety of C20,C25-diether lipids is identical with that of the C20 moiety Natronomonas pharaonis (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate - ?
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