EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.5.1.109 | dimethylallyl diphosphate + (R)-benzodiazepinedione |
low activity, (R)-benzodiazepinedione consists of a tryptophanyl and an anthranilyl moiety |
Aspergillus terreus |
diphosphate + ? |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + (S)-benzodiazepinedione |
best substrate, (S)-benzodiazepinedione consists of a tryptophanyl and an anthranilyl moiety |
Aspergillus terreus |
diphosphate + ? |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + benzodiazepinedione |
best substrate, active only with benzodiazepinedione consisting of a D-tryptophanyl and an anthranilyl moiety, poor activity with the L-Tryp isomer |
Aspergillus terreus |
diphosphate + ? |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + brevianamide F |
- |
Aspergillus versicolor |
diphosphate + deoxybrevianamide E |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + brevianamide F |
- |
Aspergillus sp. MF297-2 |
diphosphate + deoxybrevianamide E |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + brevianamide F |
the enzyme is involved in the alkaloid biosynthetic pathway |
Aspergillus sp. |
diphosphate + deoxybrevianamide E |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + brevianamide F |
the enzyme accepts a broad range of tryptophan-containing cyclic dipeptides, no activity with farnesyl diphosphate and geranyl diphosphate |
Aspergillus versicolor |
diphosphate + deoxybrevianamide E |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + brevianamide F |
the enzyme is specific for brevianamide F i.e. (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione |
Aspergillus sp. |
diphosphate + deoxybrevianamide E |
deoxybrevianamide E i.e. (3S,8aS)-3-[[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methyl]-octahydropyrrolo[1,2-a]piperazine-1,4-dione |
? |
2.5.1.109 | dimethylallyl diphosphate + brevianamide F |
i.e. cyclo-L-Trp-L-Pro |
Aspergillus versicolor |
diphosphate + deoxybrevianamide E |
- |
? |
2.5.1.109 | dimethylallyl diphosphate + brevianamide F |
i.e. cyclo-L-Trp-L-Pro, conversion yield of 66% |
Aspergillus sp. MF297-2 |
diphosphate + deoxybrevianamide E |
- |
? |