EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.5.1.108 | 5'-deoxy-5'-(3-(3-N,N-dimethylamino)phenoxy)propyl-5'-methyl-5'-thioadenosine + a protein |
- |
Pyrococcus horikoshii |
5'-deoxy-5'-(3-(3-N,N-dimethylamino)phenoxy)propyl-5'-thioadenosine + a methylated protein |
- |
? |
2.5.1.108 | 5'-deoxy-5'-(3-phenoxy)propyl-5'-methyl-5'-thioadenosine + a protein |
- |
Pyrococcus horikoshii |
5'-deoxy-5'-(3-phenoxy)propyl-5'-thioadenosine + a methylated protein |
- |
? |
2.5.1.108 | L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine |
- |
Saccharomyces cerevisiae |
2-((3S)-3-amino-3-carboxypropyl)-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine |
- |
? |
2.5.1.108 | L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine |
- |
Pyrococcus horikoshii |
2-((3S)-3-amino-3-carboxypropyl)-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine |
- |
? |
2.5.1.108 | L-histidine-[translation elongation factor 2] + S-adenosyl-L-methionine |
- |
Saccharomyces cerevisiae FY251 |
2-((3S)-3-amino-3-carboxypropyl)-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine |
- |
? |
2.5.1.108 | L-histidine-[translation elongation factor 2] + [[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl][(2E)-3-carboxyprop-2-en-1-yl]methylsulfonium |
S-adenosyl-L-methionine analogue, in which the 3-amino-3-carboxypropyl group is replaced with a 3-carboxyallyl group. The analogue is cleaved by Dph2, yielding a paramagnetic (S = 1/2) species, which is assigned to a complex formed between the reaction product, alpha-sulfinyl-3-butenoic acid, and the [4Fe-4S] cluster. Data support a pi-complex between the C=C double bond of alpha-sulfinyl-3-butenoic acid and the unique iron of the [4Fe-4S] cluster, i.e. a radical S-adenosyl-L-methionine-related [4Fe-4S]+ cluster forming an organometallic complex with an alkene |
Pyrococcus horikoshii |
2-(3-carboxyprop-2-en-1-yl)-L-histidine-[translation elongation factor 2] + S-methyl-5'-thioadenosine |
- |
? |
2.5.1.108 | more |
no activity is detected using dithionite or the Dph3/Cbr1/NADH system as the reductant |
Saccharomyces cerevisiae |
? |
- |
- |
2.5.1.108 | S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] |
- |
Saccharomyces cerevisiae |
S-methyl-5'-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] |
- |
? |
2.5.1.108 | S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] |
- |
Pyrococcus horikoshii |
S-methyl-5'-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] |
- |
? |
2.5.1.108 | S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] |
- |
Methanobrevibacter smithii |
S-methyl-5'-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2] |
- |
? |