EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.2.18 | 2-amino-2-pentenoate + 5-phospho-alpha-D-ribose 1-diphosphate |
good substrate |
Mycobacterium tuberculosis |
N-(5-phospho-D-ribosyl)-2-amino-2-pentenoate + diphosphate |
- |
? |
2.4.2.18 | 2-aminoacrylate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
Mycobacterium tuberculosis |
N-(5-phospho-D-ribosyl)-2-aminoacrylate + diphosphate |
- |
? |
2.4.2.18 | 2-aminocrotonate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
Salmonella enterica |
N-(5-phospho-D-ribosyl)-2-aminocrotonate + diphosphate |
reaction product predicted to be a phosphoribosyl-enamine adduct, which breaks down directly into phosphoribosyl amine and 2-ketobutyrate (a reaction mediated by TrpD or non-enzymatic), or which breaks down non-enzymatically into ribose 5'-phosphate, 2-ketobutyrate and NH3. Ribose 5'-phosphate and NH3 combine non-enzymatically to form phosphoribosyl amine |
? |
2.4.2.18 | 2-aminocrotonate + 5-phospho-alpha-D-ribose 1-diphosphate |
good substrate |
Mycobacterium tuberculosis |
N-(5-phospho-D-ribosyl)-2-aminocrotonate + diphosphate |
- |
? |
2.4.2.18 | ammonia + 5-phospho-alpha-D-ribose 1-diphosphate |
anthranilate synthase-phosphoribosyl transferase complex subunit TrpD in vitro |
Salmonella enterica |
phosphoribosyl amine + diphosphate |
- |
? |
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate |
- |
? |
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
Staphylococcus aureus |
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate |
- |
? |
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
Thermus thermophilus |
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate |
- |
? |
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
Escherichia coli |
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate |
- |
? |
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
Saccharomyces cerevisiae |
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate |
- |
? |