EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.312 | more |
GTDC2 generates CTD110.6 antibody-reactive N-acetylglucosamine epitopes on the O-mannosylated alpha-dystroglycan in the endoplasmic reticulum |
Homo sapiens |
? |
- |
? |
2.4.1.312 | more |
GTDC2 possesses a protein O-mannose beta-1,4-Nacetylglucosaminyltransferase activity. No substrate: UDP-GalNAc |
Homo sapiens |
? |
- |
? |
2.4.1.312 | more |
isoform POMGNT1 is promiscouos for O-mannosylated peptides |
Homo sapiens |
? |
- |
- |
2.4.1.312 | more |
isoform POMGNT2 displays significant primary amino acid selectivity near the site of O-mannosylation. In the POMGNT2 acceptor motif, arginines at -6 and -8 and an Ile at -3 position are conserved in addition to the Pro at +1 and the Thr at +2 |
Homo sapiens |
? |
- |
- |
2.4.1.312 | UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl-[IQEPPSRIVP-T-PTSPAIAPPT] |
synthetic glycopeptide derived from alpha-dystroglycan |
Homo sapiens |
UDP + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[IQEPPSRIVP-T-PTSPAIAPPT] |
- |
? |
2.4.1.312 | UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl-[PKRVRRQIHA-T-PTPVTAIGPP] |
synthetic glycopeptide derived from alpha-dystroglycan |
Homo sapiens |
UDP + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[PKRVRRQIHA-T-PTPVTAIGPP] |
- |
? |
2.4.1.312 | UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] |
- |
Homo sapiens |
UDP + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] |
- |
? |
2.4.1.312 | UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] |
synthetic acceptor, peptide corresponding to the mucin-like domain of human alpha-dystroglycan (residues 316-329), in which Thr-317 is modified by O-mannose but the remaining Thr/Ser residues are replaced with Ala |
Homo sapiens |
UDP + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] |
- |
? |
2.4.1.312 | UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl-[TIRTRGAIIQ-T-LGPIQPTR] |
synthetic glycopeptide derived from alpha-dystroglycan |
Homo sapiens |
UDP + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[TIRTRGAIIQ-T-LGPIQPTR] |
- |
? |
2.4.1.312 | UDP-N-acetyl-alpha-D-glucosamine + 3-O-(alpha-D-mannosyl)-L-threonyl-[YVEP-T-AV] |
synthetic glycopeptide derived from alpha-dystroglycan |
Homo sapiens |
UDP + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[YVEP-T-AV] |
- |
? |