EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   2.4.1.228 | more |
substrate specificity |
Homo sapiens |
? |
- |
? |
| 2.4.1.228 | more |
no substrates: galactosylceramide, glucosylceramide, neolactotetraose, neolactotetraosylceramide |
Rattus norvegicus |
? |
- |
? |
| 2.4.1.228 | more |
targeted disruption of Gb3/CD77 synthase gene results in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins |
Mus musculus |
? |
- |
? |
| 2.4.1.228 | more |
globotriaosylceramide, Gb3, is synthesized from lactosylceramide by alpha1,4-galactosyltransferase Gb3/CD77 synthase |
Homo sapiens |
? |
- |
? |
| 2.4.1.228 | more |
the consensus enzyme synthesizes both the Pk and P1 antigens, while its p.Q211E variant additionally synthesizes the NOR antigen |
Homo sapiens |
? |
- |
? |
| 2.4.1.228 | UDP-Gal + Galbeta1,4Glc-PAA |
i.e. Lac-PAA, precursor to Pk |
Homo sapiens |
UDP + ? |
- |
? |
| 2.4.1.228 | UDP-Gal + Galbeta1,4GlcNAcbeta1,3Galbeta1,4Glc-PAA |
i.e. nLc4-PAA, precursor to P1 |
Homo sapiens |
UDP + ? |
- |
? |
| 2.4.1.228 | UDP-Gal + GalNAcbeta1,3Galalpha1,4Galbeta1,4Glc-PAA |
i.e. Gbeta4-PAA, precursor to NOR1 |
Homo sapiens |
UDP + ? |
- |
? |
| 2.4.1.228 | UDP-galactose + beta-D-galactosyl-(1,4)-D-glucosylceramide |
- |
Homo sapiens |
UDP + alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide |
- |
? |
| 2.4.1.228 | UDP-galactose + beta-D-galactosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-alpha-D-galactosyl-(1,4)-beta-D-glucosylceramide |
P1 antigen synthesis |
Homo sapiens |
UDP + alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-alpha-D-galactosyl-(1,4)-beta-D-glucosylceramide |
- |
? |
