EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.186 | CDP-glucose + glycogenin |
recombinant enzyme expressed in E. coli, 71% activity compared to UDP-glucose |
Rattus norvegicus |
CDP + glucosylated glycogenin |
- |
? |
2.4.1.186 | CDP-glucose + p-nitrophenyl-alpha-maltoside |
recombinant enzyme expressed in E. coli |
Rattus norvegicus |
CDP + ? |
- |
? |
2.4.1.186 | more |
no activity with nonapeptide SISIYSYLP and N-lactosylated peptide |
Oryctolagus cuniculus |
? |
- |
? |
2.4.1.186 | more |
OsGGT-gene expression increases in FR13A (a submergence-tolerant cultivar, Indica) during submergence but decreases in IR42 (submergence-intolerant cultivar, Indica). The expression of the OsGGT gene in FR13A is induced by salicylic acid and benzyladenine. The accumulation of OsGGT mRNA in FR13A also increases in response to ethylene, gibberellin, abscisic acid, drought and salt treatment, but methyl jasmonate treatment and cold stress have no effect on expression. OsGGT gene can be related to submergence stress and associated with a general defensive response to various environmental stresses |
Oryza sativa |
? |
- |
? |
2.4.1.186 | more |
glycogenin-1 catalyzes both the glucose-O-tyrosine linkage and the alpha1,4 glucosidic bonds linking the glucose molecules in the oligosaccharide |
Homo sapiens |
? |
- |
? |
2.4.1.186 | more |
human glycogenin during its reaction cycle shows a dynamic conformational switch between ground and active states mediated by the sugar donor UDP-glucose. This switch includes the ordering of a polypeptide stretch containing Tyr195, and major movement of an approximately 30-residue lid segment covering the active site. The rearranged lid guides the nascent maltosaccharide chain into the active site in either an intra- or intersubunit mode dependent upon chain length and steric factors and positions the donor and acceptor sugar groups for catalysis. Mapping of donor and acceptor subsites in hGYG1, overview |
Homo sapiens |
? |
- |
? |
2.4.1.186 | more |
glycosylated HLPFIYNLSSNTMYTYSPAFK peptide products originating from glycogenin-2, mass spectrometric analysis, overview |
Homo sapiens |
? |
- |
? |
2.4.1.186 | more |
the enzyme performs autoglucosylation |
Homo sapiens |
? |
- |
- |
2.4.1.186 | more |
the enzyme performs autoglucosylation |
Mus musculus |
? |
- |
- |
2.4.1.186 | TDP-glucose + glycogenin |
recombinant enzyme expressed in E. coli, 33% activity compared to UDP-glucose |
Rattus norvegicus |
TDP + glucosylated glycogenin |
- |
? |