EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.149 | Galbeta(1->4)GlcNAcbeta(1->3)[Galbeta(1->4)GlcNAcbeta(1->6)]GalNAcalpha-OCH(CH3)CH(NH2)CO2H |
115% activity compared to Galbeta(1->4)GlcNAcbeta-O(CH2)3N3 |
Helicobacter pylori |
UDP + GlcNAcbeta(1->3)Galbeta(1->4)GlcNAcbeta(1->3)[Galbeta(1->4)GlcNAcbeta(1->6)]GalNAcalpha-OCH(CH3)CH(NH2)CO2H |
- |
? |
2.4.1.149 | more |
no acceptors: melibiose, gentiobiose, galactose, glucose, N-acetylgalactosamine, N-acetylglucosamine |
Homo sapiens |
? |
- |
? |
2.4.1.149 | more |
asialo-serum glycoproteins are much more effective than O-glycoproteins as acceptors, overview over oligosaccharide substrates |
Rattus norvegicus |
? |
- |
? |
2.4.1.149 | more |
transfer of GlcNAc occurs mainly to type 2 chain nonfucosylated structures, elongation of type 1 chain structure Lc4 is also detectable, no transfer to any fucosylated derivative of either type 1 or 2 chains, transfer of GlcNAc to a terminal Gal residue on a lacto-series core chain |
Homo sapiens |
? |
- |
? |
2.4.1.149 | more |
terminal Galbeta(1-4)Glc(NAc) sequences, i.e. type II chains, are preferred substrates, no substrates: terminal Galbeta(1-3)GlcNAc sequences, i.e. type I chains, Lewis X trisaccharides, i.e. Galbeta(1-4)(Fucalpha(1-3))GlcNAc, monosaccharides, e.g. galactose, asialo-bovine submaxillary mucin that contains GalNAcalpha1-Ser/Thr and Galbeta(1-3)GalNAcalpha1-Ser/Thr |
Bos taurus |
? |
- |
? |
2.4.1.149 | more |
no acceptor: Galbeta(1-3)GlcNAcbeta(1-3)Galbeta(1-4)Glc |
Homo sapiens |
? |
- |
? |
2.4.1.149 | more |
biosynthesis of lacto-series core chains, enzyme is activated in association with oncogenesis in colonic epithelia |
Homo sapiens |
? |
- |
? |
2.4.1.149 | more |
beta3GnT7 may play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues |
Mus musculus |
? |
- |
? |
2.4.1.149 | more |
the enzyme together with N-acetyllactosamine synthase, EC 2.4.1.90, catalyzes formation of linear glycans containing alternating beta-3-O-substituted residues of D-galactose and beta-4-O-substituted residues of N-acetyl-D-glucosamine, structures are present among others in glycosphingolipids or H-II type, polyglycosylceramides and polyglycosylpeptides, e.g. erythroglycan |
Homo sapiens |
? |
- |
? |
2.4.1.149 | more |
biosynthesis of Ii core glycosphingolipids |
Mus musculus |
? |
- |
? |