EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.1.211 | 2 4-coumaroyl-CoA + malonyl-CoA + H2O |
- |
Oryza sativa |
3 CoA + bisdemethoxycurcumin + 2 CO2 |
- |
? |
2.3.1.211 | 2 4-coumaroyl-CoA + malonyl-CoA + H2O |
- |
Curcuma longa |
3 CoA + bisdemethoxycurcumin + 2 CO2 |
- |
? |
2.3.1.211 | 2 4-coumaroyl-CoA + malonyl-CoA + H2O |
- |
Oryza sativa Japonica Group |
3 CoA + bisdemethoxycurcumin + 2 CO2 |
- |
? |
2.3.1.211 | 2 4-coumaroyl-CoA + malonyl-CoA + H2O |
- |
Oryza sativa |
3 CoA + bisdemethoxycurcumin + 2 CO2 |
a minor product is a triketide pyrone formed from one 4-coumaroyl-CoA and two malonyl-CoAs. No formation of 5-(4-hydroxyphenyl)-3-oxo-pent-4-enoic acid and 4-hydroxybenzalacetone |
? |
2.3.1.211 | 2 4-coumaroyl-CoA + malonyl-CoA + H2O |
curcuminoid synthase catalyzes the formation of diketide-CoA by condensing 4-coumaroyl-CoA and malonyl-CoA. The resulting diketide-CoA is hydrolyzed and converted to a beta-keto acid. Finally, curcuminoid synthase catalyzes a decarboxylative condensation of the beta-keto acid with another molecule of 4-coumaroyl-CoA, to synthesize curcuminoid |
Oryza sativa |
3 CoA + bisdemethoxycurcumin + 2 CO2 |
- |
? |
2.3.1.211 | 2 4-coumaroyl-CoA + malonyl-CoA + H2O |
the reaction proceeds in three steps via formation of 4-coumaroyldiketide-CoA and 4-coumaroyl beta-keto acid, overview |
Oryza sativa |
3 CoA + bisdemethoxycurcumin + 2 CO2 |
- |
? |
2.3.1.211 | 2 cinnamoyl-CoA + malonyl-CoA + H2O |
- |
Oryza sativa |
3 CoA + dicinnamoylmethane + 2 CO2 |
- |
? |
2.3.1.211 | 2 feruloyl-CoA + malonyl-CoA + H2O |
- |
Oryza sativa |
3 CoA + curcumin + 2 CO2 |
- |
? |
2.3.1.211 | 2 feruloyl-CoA + malonyl-CoA + H2O |
the reaction proceeds in three steps via formation of feruloyldiketide-CoA and feruloyl beta-keto acid, overview |
Oryza sativa |
3 CoA + curcumin + 2 CO2 |
- |
? |
2.3.1.211 | 2 feruloyl-CoA + malonyl-CoA + H2O |
very low activity |
Oryza sativa |
3 CoA + 4-hydroxy-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2H-pyran-2-one + curcumin |
- |
? |