EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.1.176 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA |
- |
Mus musculus |
CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA |
- |
? |
2.3.1.176 | more |
SCP-2, significantly enhances disruption of the dihydroergosterol microcrystalline structure when in the presence of excess cholesterol. In experiments with model membranes containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, cholesterol, and 1,2-dioleoylsn-glycero-3-[phospho-L-serine], SCP-2 enhances exchange of sterol between microcrystals and large unilamellar vesicles nearly 92fold more in the initial rate than the spontaneous exchange |
Homo sapiens |
? |
- |
? |
2.3.1.176 | more |
recombinant MsSCP-2 binds to NBD-cholesterol with high affinity, which is suppressed by sterol carrier protein-2 inhibitors |
Manduca sexta |
? |
- |
? |