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EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
2.3.1.160	11-methoxy-16-epivellosimine + acetyl-CoA	-	Rauvolfia serpentina	CoA + 11-methoxy-vinorine	-	?
2.3.1.160	16-epi-vellosimine + acetyl-CoA	VS responsible for generation of the basic carbon skeleton of the target compound ajmaline, His160 and Asp164 are the most important amino acids for the catalytic process, His-X-X-X-Asp sequence together with Asp-Phe-Gly-Trp-Gly are highly conserved motifs in acyltransferases	Rauvolfia serpentina	vinorine + CoA	-	?
2.3.1.160	acetyl-CoA + 16-epivellosimine	-	Rauvolfia serpentina	CoA + vinorine	-	?
2.3.1.160	acetyl-CoA + 16-epivellosimine	-	Rauvolfia serpentina	CoA + vinorine	-	r
2.3.1.160	acetyl-CoA + 16-epivellosimine	the enzyme is involved in a crucial step of antiarrhythmic drug ajmaline biosynthesis, pathway overview	Rauvolfia serpentina x Rhazya stricta	CoA + vinorine	-	?
2.3.1.160	acetyl-CoA + 16-epivellosimine	the enzyme is involved in a crucial step of antiarrhythmic drug ajmaline biosynthesis, pathway overview	Rauvolfia serpentina x Rhazya stricta	CoA + vinorine	-	r
2.3.1.160	acetyl-CoA + 16-epivellosimine	the enzyme is involved in a crucial step of antiarrhythmic drug ajmaline biosynthesis, pathway overview	Rauvolfia serpentina	CoA + vinorine	-	r
2.3.1.160	acetyl-CoA + 16-epivellosimine	substrate specificity in both reaction directions, the reverse reaction is preferred	Rauvolfia serpentina x Rhazya stricta	CoA + vinorine	-	r
2.3.1.160	acetyl-CoA + 16-epivellosimine	the forward reaction is preferred	Rauvolfia serpentina x Rhazya stricta	CoA + vinorine	-	r
2.3.1.160	acetyl-CoA + gardneral	i.e. 11-methoxy-16-epivellosimine, sarpagan-type alkaloid	Rauvolfia serpentina x Rhazya stricta	CoA + 11-methoxyvinorine	ajmalin-type alkaloid	r

Results 1 - 10 of 13

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Release 2023.1 (January 2023)