EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.46 | more |
no methylation of: p-hydroxycinnamic acid, p-hydroxybenzoic acid, 3,4-dihydroxycinnamic acid, naringenin, (5,7,4'-trihydroxyflavanone), apigenin (5,7,4'-trihydroxyflavone), luteolin (5,7,3',4'-tetrahydroxyflavone), kaempferol (3,5,7,4'-tetrahydroxyflavone), wedelolactone (5,3',4'-trihydroxy-7-methoxycoumestone) |
Cicer arietinum |
? |
- |
? |
2.1.1.46 | more |
the bifunctionally enzyme also catalyzes the formation of a 2,7-dihydroxy-4'-methoxyisoflavanone from a 2,4',7-trihydroxyisoflavanone (reaction of EC 2.1.1.212) |
Glycyrrhiza uralensis |
? |
- |
- |
2.1.1.46 | more |
the enzyme is not able to methylate 2,7,4'-trihydroxyisoflavanone, biochanin A, formononetin, apigenin, luteolin, liquirtitigenin, kaempferol, quercetin, isoliquiritigenin, and caffeic acid |
Pueraria montana var. lobata |
? |
- |
- |
2.1.1.46 | S-adenosyl-L-methionine + 5,7,4'trihydroxyisoflavone |
- |
Cicer arietinum |
S-adenosyl-L-homocysteine + 5,7-dihydroxy-4'-O-methylisoflavone |
- |
? |
2.1.1.46 | S-adenosyl-L-methionine + 7,4'-dihydroxyisoflavone |
i.e. daidzein. Methylation is the last step in the biosynthesis of 4-methoxyisoflavones |
Cicer arietinum |
S-adenosyl-L-homocysteine + 7-hydroxy-4'-O-methylisoflavone |
- |
? |
2.1.1.46 | S-adenosyl-L-methionine + 7,4'-dihydroxyisoflavone |
i.e. daidzein. Methylation is the last step in the biosynthesis of 4'-methoxyisoflavones |
Cicer arietinum |
S-adenosyl-L-homocysteine + 7-hydroxy-4'-O-methylisoflavone |
- |
? |
2.1.1.46 | S-adenosyl-L-methionine + 7,4'-dihydroxyisoflavone |
i.e. daidzein. The reaction follows an ordered BiBi mechanism with S-adenosylmethionine and S-adenosylhomocysteine as leading reaction partners |
Cicer arietinum |
S-adenosyl-L-homocysteine + 7-hydroxy-4'-methoxylisoflavone |
- |
? |
2.1.1.46 | S-adenosyl-L-methionine + a 4'-hydroxyisoflavone |
- |
Glycyrrhiza uralensis |
S-adenosyl-L-homocysteine + a 4'-methoxyisoflavone |
- |
? |
2.1.1.46 | S-adenosyl-L-methionine + daidzein |
- |
Glycyrrhiza uralensis |
S-adenosyl-L-homocysteine + formononetin |
- |
? |
2.1.1.46 | S-adenosyl-L-methionine + daidzein |
48.8% activity compared to genistein |
Pueraria montana var. lobata |
S-adenosyl-L-homocysteine + formononetin |
- |
? |