EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    2.1.1.116 | more |
the enzyme is central to the biosynthesis of tetrahydroisoquinoline-derived alkaloids |
Papaver somniferum |
? |
- |
? |
| 2.1.1.116 | more |
only tetrahydroxylated tetrahydrobenzylisoquinolines are accepted as substrates, methylation is tolerated only at the 6-hydroxy position, no methylation when catechol and guaiacol or the phenylpropanoids caffeic and ferulic acid are used as substrate |
Papaver somniferum |
? |
- |
? |
| 2.1.1.116 | more |
no activity with norcoclaurine, coclaurine, N-methylcoclaurine, reticuline, scoulerine, and tetrahydrocolumbamine |
Coptis chinensis |
? |
- |
? |
| 2.1.1.116 | S-adenosyl-L-homocysteine + (S)-reticuline |
- |
Eschscholzia californica |
S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine |
- |
? |
| 2.1.1.116 | S-adenosyl-L-homocysteine + (S)-reticuline |
- |
Coptis japonica |
S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine |
- |
? |
| 2.1.1.116 | S-adenosyl-L-methionine + (R,S)-3'-hydroxy-N-methylcoclaurine |
- |
Papaver somniferum |
? |
- |
? |
| 2.1.1.116 | S-adenosyl-L-methionine + (R,S)-6-O-methylnorlaudanosoline |
- |
Papaver somniferum |
? |
- |
? |
| 2.1.1.116 | S-Adenosyl-L-methionine + (R,S)-7-O-methyllaudanosoline |
93% of the activity relative to 3'-hydroxy-N-methyl-(S)-coclaurine |
Berberis koetineana |
S-Adenosyl-L-homocysteine + norprotosinomenine |
- |
? |
| 2.1.1.116 | S-Adenosyl-L-methionine + (R,S)-laudanosoline |
84% of the activity relative to 3'-hydroxy-N-methyl-(S)-coclaurine |
Berberis koetineana |
S-Adenosyl-L-homocysteine + 4'-O-methyllaudanosoline |
- |
? |
| 2.1.1.116 | S-adenosyl-L-methionine + (R,S)-laudanosoline |
- |
Papaver somniferum |
? |
- |
? |
