EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.3.7.11 | 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + reduced acceptor |
the enzyme is involved in the biosynthesis of archaeal membrane lipids |
Sulfolobus acidocaldarius |
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + acceptor |
- |
? |
1.3.7.11 | 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + reduced acceptor |
the enzyme is involved in the biosynthesis of archaeal membrane lipids |
Archaeoglobus fulgidus |
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + acceptor |
- |
? |
1.3.7.11 | 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + reduced acceptor |
most preferred substrate. Since the physiological reducing agents for the enzyme remains unknown, sodium dithionite is used as acceptor |
Sulfolobus acidocaldarius |
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + acceptor |
- |
? |
1.3.7.11 | 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + reduced acceptor |
the enzyme shows a preference for 2,3-di-O-geranylgeranylglyceryl phosphate over 3-O-geranylgeranylglyceryl phosphate and geranylgeranyl diphosphate in vitro |
Archaeoglobus fulgidus |
2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + acceptor |
- |
? |
1.3.7.11 | 2,3-di-O-geranylgeranylglyceryl phosphate + 16 reduced ferredoxin [iron-sulfur] cluster + 16 H+ |
- |
Thermoplasma acidophilum |
2,3-di-O-phytanylglyceryl phosphate + 16 oxidized ferredoxin [iron-sulfur] cluster |
- |
? |
1.3.7.11 | 3-O-geranylgeranyl-sn-glycerol 1-phosphate + reduced acceptor |
activity is comparable to the activity with 2,3-di-O-geranylgeranyl-sn-glycerol 1-phosphate as substrate |
Sulfolobus acidocaldarius |
3-O-phytyl-sn-glycerol 1-phosphate + acceptor |
- |
? |
1.3.7.11 | 3-O-geranylgeranyl-sn-glycerol 1-phosphate + reduced acceptor |
the enzyme shows a preference for 2,3-di-O-geranylgeranylglyceryl phosphate over 3-O-geranylgeranylglyceryl phosphate and geranylgeranyl diphosphate in vitro |
Archaeoglobus fulgidus |
? |
- |
? |
1.3.7.11 | a 2,3-bis-(O-geranylgeranyl)-sn-glycero-phospholipid + 16 dithionite + 16 H+ |
i.e. DGGGP-glycerol |
Methanosarcina acetivorans |
a 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid + 16 oxidized dithionite |
- |
? |
1.3.7.11 | a 2,3-bis-(O-geranylgeranyl)-sn-glycero-phospholipid + 16 dithionite + 16 H+ |
i.e. DGGGP-glycerol |
Methanosarcina acetivorans DSM 2834 |
a 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid + 16 oxidized dithionite |
- |
? |
1.3.7.11 | a 2,3-bis-(O-geranylgeranyl)-sn-glycero-phospholipid + 16 reduced ferredoxin [iron-sulfur] cluster + 16 H+ |
- |
Thermoplasma acidophilum |
a 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid + 16 oxidized ferredoxin [iron-sulfur] cluster |
- |
? |