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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.2.1.41
acetaldehyde + NAD+ + H2O
-
Mus musculus
acetate + NADH + H+
-
?
1.2.1.41
glutamate gamma-semialdehyde + NAD+ + H2O
-
Homo sapiens
L-glutamate + NADH + H+
-
?
1.2.1.41
L-5-glutamyl phosphate + NADPH
second enzyme in pathway of proline biosynthesis
Escherichia coli
?
-
?
1.2.1.41
L-5-glutamyl phosphate + NADPH
gamma-glutamyl kinase (the first enzyme of proline biosynthetic pathway) and gamma-glutamyl phosphate reductase (second enzyme) form a complex which stabilizes the labile intermediate i.e. gamma-glutamyl phosphate
Escherichia coli
?
-
?
1.2.1.41
L-glutamate 5-semialdehyde + phosphate + NAD+
-
Thermus thermophilus
L-glutamyl 5-phosphate + NADH + H+
-
?
1.2.1.41
L-glutamate 5-semialdehyde + phosphate + NADP+
-
Salmonella enterica subsp. enterica serovar Typhimurium
L-5-glutamyl phosphate + NADPH
-
?
1.2.1.41
L-glutamate 5-semialdehyde + phosphate + NADP+
-
Escherichia coli
L-5-glutamyl phosphate + NADPH
-
?
1.2.1.41
L-glutamate 5-semialdehyde + phosphate + NADP+
-
Escherichia coli
L-5-glutamyl phosphate + NADPH
-
r
1.2.1.41
L-glutamate 5-semialdehyde + phosphate + NADP+
-
Pseudomonas aeruginosa
L-5-glutamyl phosphate + NADPH
-
?
1.2.1.41
L-glutamate 5-semialdehyde + phosphate + NADP+
L-glutamate 5-semialdehyde spontaneously cyclizes to delta-1-pyrroline-5-carboxylic acid
Rattus norvegicus
L-5-glutamyl phosphate + NADPH
-
?
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