EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.19.67 | (R)-norreticuline + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Papaver somniferum |
norsalutaridine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.19.67 | (R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Papaver somniferum |
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.19.67 | (R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 |
highly regioselective and stereoselective enzyme |
Sus scrofa |
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.19.67 | (R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 |
strictly dependent on NADPH as reducing cofactor and on (R)-configurated reticuline |
Papaver somniferum |
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.19.67 | (R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 |
formation of salutaridine, a key intermediate in morphine biosynthesis |
Papaver somniferum |
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.19.67 | (R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 |
critical step in morphine biosynthesis |
Sus scrofa |
salutaridine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.19.67 | (R)-reticuline + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Papaver somniferum |
salutaridine + [oxidized NADPH-hemoprotein reductase] + 2 H2O |
- |
? |
1.14.19.67 | (R/S)-orientaline + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Sus scrofa |
? |
- |
? |