EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    1.14.15.4 | 11-deoxy-cortisol + reduced ferredoxin + O2 |
- |
Rattus norvegicus |
cortisol + ferredoxin + H2O |
- |
? |
| 1.14.15.4 | 11-deoxycorticosterone + adrenal ferredoxin + H2O |
- |
Homo sapiens |
corticosterone + reduced adrenal ferredoxin + O2 |
- |
? |
| 1.14.15.4 | 11-deoxycorticosterone + NADPH + O2 |
- |
Rattus norvegicus |
18-hydroxycorticosterone + NADP+ + H2O |
- |
? |
| 1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + 2 H+ + 2 O2 |
- |
Bos taurus |
aldosterone + oxidized adrenal ferredoxin + 2 H2O |
- |
? |
| 1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + 2 H+ + 2 O2 |
supported by adrenodoxin and adrenodoxin reductase, 3 step-hydroxylation with corticosterone and 18-hydroxycorticosterone as intermediates, 11beta-/18-hydroxylase |
Sus scrofa |
aldosterone + oxidized adrenal ferredoxin + 2 H2O |
- |
? |
| 1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + 2 H+ + 2 O2 |
11beta-hydroxylase and 18-hydroxylase activities, after replacement of Tween 20 by phosphatidylcholine catalytic activity for aldosterone activity is exhibited, form 1 higher active in aldosterone and 18-hydroxycorticosterone production and less active in the production of corticosterone and 18-hydroxydeoxycorticosterone from deoxycorticosterone as form 2 |
Bos taurus |
aldosterone + oxidized adrenal ferredoxin + 2 H2O |
- |
? |
| 1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + 2 H+ + 2 O2 |
49 kDa protein, exclusively in zona glomerulosa, 11beta -hydroxylation, as well as 18-hydroxylation and 18-hydroxydehydrogenation of corticosterone with 18-hydroxydeoxycorticosterone and 18-hydroxycorticosterone as intermediates |
Rattus norvegicus |
aldosterone + oxidized adrenal ferredoxin + 2 H2O |
- |
? |
| 1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + 2 H+ + 2 O2 |
49 kDa protein, exclusively in zona glomerulosa, 11beta -hydroxylation, as well as 18-hydroxylation and 18-hydroxydehydrogenation of corticosterone with 18-hydroxydeoxycorticosterone and 18-hydroxycorticosterone as intermediates |
Rattus norvegicus |
aldosterone + oxidized adrenal ferredoxin + 2 H2O |
product of 49 kDa protein |
? |
| 1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + 2 H+ + 2 O2 |
51 kDa protein, zona fasciculata and glomerulosa, high sodium and low potassium, 11beta-/18-hydroxylation |
Rattus norvegicus |
aldosterone + oxidized adrenal ferredoxin + 2 H2O |
product of 49 kDa protein |
? |
| 1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + 2 H+ + 2 O2 |
11beta-/18-hydroxylation |
Bos taurus |
aldosterone + oxidized adrenal ferredoxin + 2 H2O |
- |
? |
