EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.15.29 | (25S)-25-bromo-27-norcholesterol + 6 reduced [2Fe-2S] ferredoxin + 3 O2 |
- |
Mycobacterium tuberculosis |
(25S)-25-bromo-27-norcholesterol-26-oate + 6 oxidized [2Fe-2S] ferredoxin + 4 H2O |
- |
? |
1.14.15.29 | (25S)-25-bromo-27-norcholesterol + 6 reduced [2Fe-2S] ferredoxin + 3 O2 |
- |
Mycobacterium tuberculosis H37Rv |
(25S)-25-bromo-27-norcholesterol-26-oate + 6 oxidized [2Fe-2S] ferredoxin + 4 H2O |
- |
? |
1.14.15.29 | 26-methylcholesterol + 6 reduced [2Fe-2S] ferredoxin + 3 O2 |
- |
Mycobacterium tuberculosis |
(25S)-3beta-hydroxycholest-5-en-27-oate + 6 oxidized [2Fe-2S] ferredoxin + 4 H2O |
- |
? |
1.14.15.29 | 26-methylcholesterol + 6 reduced [2Fe-2S] ferredoxin + 3 O2 |
- |
Mycobacterium tuberculosis H37Rv |
(25S)-3beta-hydroxycholest-5-en-27-oate + 6 oxidized [2Fe-2S] ferredoxin + 4 H2O |
- |
? |
1.14.15.29 | 27-hydroxycholest-4-en-3-one + 4 reduced ferredoxin [iron-sulfur] cluster + 4 H+ + O2 |
- |
Mycobacterium tuberculosis |
cholest-4-en-3-one-27-oic acid + 4 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O |
- |
? |
1.14.15.29 | 27-hydroxycholest-4-en-3-one + 4 reduced ferredoxin [iron-sulfur] cluster + 4 H+ + O2 |
- |
Mycobacterium tuberculosis CDC 1551 |
cholest-4-en-3-one-27-oic acid + 4 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O |
- |
? |
1.14.15.29 | 7alpha-hydroxycholest-4-en-3-one + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+ + 3 O2 |
- |
Mycolicibacterium smegmatis |
(25S)-7alphahydroxy-3-oxocholest-4-en-26-oate + 6 oxidized ferredoxin [iron-sulfur] cluster + 4 H2O |
- |
? |
1.14.15.29 | 7alpha-hydroxycholest-4-en-3-one + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+ + 3 O2 |
- |
Mycolicibacterium smegmatis ATCC 700084 |
(25S)-7alphahydroxy-3-oxocholest-4-en-26-oate + 6 oxidized ferredoxin [iron-sulfur] cluster + 4 H2O |
- |
? |
1.14.15.29 | cholest-4-en-3-one + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 |
physiological substrate, the enzyme hydroxylates cholest-4-en-3-one at C-27 |
Mycobacterium tuberculosis |
27-hydroxycholest-4-en-3-one + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O |
- |
? |
1.14.15.29 | cholest-4-en-3-one + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 |
physiological substrate, the enzyme hydroxylates cholest-4-en-3-one at C-27 |
Mycobacterium tuberculosis CDC 1551 |
27-hydroxycholest-4-en-3-one + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O |
- |
? |