EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.162 | (2S)-liquiritigenin + [reduced NADPH-hemoprotein reductase] + O2 |
hydroxylation of liquiritigenin at C-2 and formation of licodione as a result of non-enzymatic hemiacetal opening, selectivity towards (2S)-flavanone |
Glycyrrhiza echinata |
licodione + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.162 | (2S)-liquiritigenin + [reduced NADPH-hemoprotein reductase] + O2 |
requires NAD(P)H and O2 for activity, the reaction mechanism is likely to be 2-hydroxylation of the flavanone molecule to yield 2-hydroxyliquiritigenin and the subsequent hemiacetal opening to give licodione, introduces one atom of oxygen into the substrate, NADH serves as hydride donor less effectively than NADPH |
Glycyrrhiza echinata |
licodione + [oxidized NADPH-hemoprotein reductase] + H2O |
i.e. 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1,3-propanedione |
? |
1.14.14.162 | (2S)-liquiritigenin + [reduced NADPH-hemoprotein reductase] + O2 |
requires NAD(P)H and O2 for activity, the reaction mechanism is likely to be 2-hydroxylation of the flavanone molecule to yield 2-hydroxyliquiritigenin and the subsequent hemiacetal opening to give licodione, introduces one atom of oxygen into the substrate, NADPH serves as hydride donor more effectively than NADH |
Glycyrrhiza echinata |
licodione + [oxidized NADPH-hemoprotein reductase] + H2O |
i.e. 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1,3-propanedione |
? |
1.14.14.162 | (2S)-naringenin + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Glycyrrhiza echinata |
2-hydroxynaringenin + [oxidized NADPH-hemoprotein reductase] + H2O |
the product is further converted into apigenin when treated with acid |
? |
1.14.14.162 | (2S)-naringenin + [reduced NADPH-hemoprotein reductase] + O2 |
selectivity towards (2S)-flavanone |
Glycyrrhiza echinata |
2-hydroxynaringenin + [oxidized NADPH-hemoprotein reductase] + H2O |
the product is further converted into apigenin when treated with HCl |
? |
1.14.14.162 | eriodictyol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Glycyrrhiza echinata |
luteolin + [oxidized NADPH-hemoprotein reductase] + H2O |
product is formed after acid treatment |
? |
1.14.14.162 | eriodictyol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Oryza sativa Japonica Group |
2-hydroxyeriodictyol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.162 | eriodictyol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Oryza sativa |
2-hydroxyeriodictyol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.162 | more |
flavone biosynthesis |
Glycyrrhiza echinata |
? |
- |
? |
1.14.14.162 | more |
involved in flavonoid biosynthesis, may play a role symbiotic plant-microbe interactions |
Glycyrrhiza echinata |
? |
- |
? |