EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.154 | (3b,4a,5a)-4,14-dimethylcholest-8-en-3-ol + [reduced NADPH-hemoprotein reductase] + O2 |
good substrate, 67% of activity compared to obtusifoliol |
Zea mays |
? + formate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.154 | (3beta,4alpha,5alpha)-4,14-dimethylcholest-8-en-3-ol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Zea mays |
? |
- |
r |
1.14.14.154 | 14alpha-methyl-24,28-dihydrofecosterol + [reduced NADPH-hemoprotein reductase] + O2 |
50% of activity compared to obtusifoliol |
Zea mays |
? + formate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.154 | 14alpha-methylzymosterol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Leishmania mexicana |
? |
- |
? |
1.14.14.154 | 14alpha-methylzymosterol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Leishmania infantum |
? |
- |
? |
1.14.14.154 | 2-phenylimidazole + [reduced NADPH-hemoprotein reductase] + O2 |
2-phenylimidazole binding causes thermally induced alterations in CYP51 active site structure and/or binding modes for the small ligand |
Mycobacterium tuberculosis |
? |
- |
? |
1.14.14.154 | 24(28)-methylene-24,25-dihydrolanosterol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Cryptococcus neoformans |
4,4-dimethyl-ergosta-8,14,24(28)-trien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.154 | 24,25-dihydrolanosterol + [reduced NADPH-hemoprotein reductase] + O2 |
8-lanosta-3beta-ol |
Homo sapiens |
4,4-dimethyl-5alpha-cholesta-8,14-dien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.154 | 24,25-dihydrolanosterol + [reduced NADPH-hemoprotein reductase] + O2 |
8-lanosta-3beta-ol |
Rattus norvegicus |
4,4-dimethyl-5alpha-cholesta-8,14-dien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.154 | 24,25-dihydrolanosterol + [reduced NADPH-hemoprotein reductase] + O2 |
8-lanosta-3beta-ol |
Saccharomyces cerevisiae |
4,4-dimethyl-5alpha-cholesta-8,14-dien-3beta-ol + formate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |