EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.150 | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Helianthus annuus |
(+)-costunolide + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.150 | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Cichorium intybus |
(+)-costunolide + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.150 | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Lactuca sativa |
(+)-costunolide + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.150 | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Cichorium intybus |
(+)-costunolide + [oxidized NADPH-hemoprotein reductase] + H2O |
(+)-costunolide is detected as its Cope rearrangement product dehydrosaussurea lactone |
ir |
1.14.14.150 | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Helianthus annuus |
(+)-costunolide + [oxidized NADPH-hemoprotein reductase] + 2 H2O |
- |
? |
1.14.14.150 | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Cynara cardunculus var. altilis |
(+)-costunolide + [oxidized NADPH-hemoprotein reductase] + 2 H2O |
- |
? |
1.14.14.150 | germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Tanacetum parthenium |
(+)-costunolide + [oxidized NADPH-hemoprotein reductase] + 2 H2O |
- |
? |
1.14.14.150 | more |
(+)-costunolide synthase is a cytochrome P450 enzyme |
Cichorium intybus |
? |
- |
? |
1.14.14.150 | more |
(+)-costunolide synthase is not capable of converting alpha-costic acid and elema-1,3,11(13)-trien-12-oic acid |
Cichorium intybus |
? |
- |
? |