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Results 1 - 6 of 6
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.138lithocholate + [reduced NADPH-hemoprotein reductase] + O2 - Rattus norvegicus 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.138lithocholate + [reduced NADPH-hemoprotein reductase] + O2 - Mesocricetus auratus 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.138lithocholate + [reduced NADPH-hemoprotein reductase] + O2 a STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase gene expression by growth hormone Mesocricetus auratus 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.138lithocholate + [reduced NADPH-hemoprotein reductase] + O2 in male hamsters, 6beta-hydroxylation is the major pathway for detoxification of lithocholate. Likely CYP3A10 is responsible for this activity Mesocricetus auratus 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.138lithocholate + [reduced NADPH-hemoprotein reductase] + O2 the male-specific P450 catalyzes the reaction. The pattern of growth hormone secretion is directly responsible for male-specific expression of this gene. STAT 5a and STAT 5b mediates GH-dependent regulation of CYP3A10/6beta-hydroxylase promoter activity Mesocricetus auratus 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.138more hydroxylations of bile acids by reconstituted systems from rat liver microsomes Rattus norvegicus ? - ?
Results 1 - 6 of 6
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