EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.127 | (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Tribolium castaneum |
? + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Epicauta chinensis |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Blattella germanica |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Melipona scutellaris |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Bombus terrestris terrestris |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Locusta migratoria |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
2E,6E isomer, product has 10R configuration |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Tribolium castaneum |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
product has (10R)-configuration |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
the enzyme, found in insects except for Lepidoptera (moths and butterflies) is specific for methyl farnesoate |
Diploptera punctata |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
the enzyme is specific for methyl (2E,6E)-farnesoate i.e. (2E,6E)-3,7,11-trimethyl-2,6-dodecatrienoate. The enzyme produces juvenile hormone III with a ratio of 98:2 in favor of the natural (10R)-epoxide enantiomer. No activity with methyl (2Z,6Z)-farnesoate, methyl (2Z,6E)-farnesoate |
Diploptera punctata |
juvenile hormone III + [oxidized NADPH-hemoprotein reductase] + H2O |
juvenile hormone III i.e. methyl (2E,6E,10R,11S)-10,11-epoxy-3,7,11-trimethyldodeca-2,6-dienoate |
? |
1.14.14.127 | methyl (2E,6E)-farnesoate + [reduced NADPH-hemoprotein reductase] + O2 |
epoxidation is 12% compared to epoxidation of methyl (2E,6E)-farnesoate |
Diploptera punctata |
? |
- |
? |