EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.106 | taxa-4(20),11(12)-dien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus sp. |
taxa-4(20),11(12)-dien-5alpha-yl-acetyl-13alpha-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
product identification and quantification by HPLC and GC-MS |
? |
1.14.14.106 | taxa-4(20),11(12)-dien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
step in taxol biosynthesis, metabolite analysis and pathway overview |
Taxus sp. |
taxa-4(20),11(12)-dien-5alpha-yl-acetyl-13alpha-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.106 | taxa-4(20),11-dien-5alpha-ol + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus cuspidata |
taxa-4(20),11-dien-5alpha,13alpha-diol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.106 | taxa-4(20),11-dien-5alpha-yl-acetate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus cuspidata |
taxa-4(20),11-dien-5alpha,13alpha-diol-5-acetate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.106 | taxa-4(20),11-dien-5alpha-yl-acetate + [reduced NADPH-hemoprotein reductase] + O2 |
6% of activity with taxa-4(20),11-dien-5alpha-ol |
Taxus cuspidata |
taxa-4(20),11-dien-5alpha,13alpha-diol-5-acetate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.106 | taxadien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
the enzyme is involved in the taxol biosynthetic pathway, overview |
Taxus cuspidata |
taxa-4(20),11(12)-dien-5alpha-yl-acetyl-13alpha-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.106 | taxadien-5alpha-yl acetate + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Taxus cuspidata |
taxa-4(20),11-dien-5alpha-yl-acetyl-13alpha-ol + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |