EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   1.14.14.103 | 2,3-dihydro-3-hydroxytabersonine + [reduced NADPH-hemoprotein reductase] + O2 |
low activity |
Catharanthus roseus |
2,3-dihydro-3,16-dihydroxytabersonine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
| 1.14.14.103 | 2,3-dihydrotabersonine + [reduced NADPH-hemoprotein reductase] + O2 |
low activity |
Catharanthus roseus |
2,3-dihydro-16-hydroxytabersonine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
| 1.14.14.103 | more |
alkaloid and enzymatic profiling of the vindoline biosynthetic pathway, overview |
Catharanthus roseus |
? |
- |
? |
| 1.14.14.103 | more |
the enzyme is involved in biosynthesis of precursors in the vindoline pathway in Catharanthus roseus leaf epidermal cells, biosynthesis of anticancer dimeric alkaloids vinblastine and vincristine, overview |
Catharanthus roseus |
? |
- |
? |
| 1.14.14.103 | more |
no activity with naringenin, tryptamine, secologanin, strictosidine, ajmalicine, vindoline, and catharanthine |
Catharanthus roseus |
? |
- |
? |
| 1.14.14.103 | tabersonine + NADPH + H+ + O2 |
- |
Catharanthus roseus |
16-hydroxytabersonine + NADP+ + H2O |
- |
? |
| 1.14.14.103 | tabersonine + NADPH + H+ + O2 |
highest activity |
Catharanthus roseus |
16-hydroxytabersonine + NADP+ + H2O |
- |
? |
| 1.14.14.103 | tabersonine + NADPH + H+ + O2 |
NADH is less active as substrate |
Catharanthus roseus |
16-hydroxytabersonine + NADP+ + H2O |
- |
? |
| 1.14.14.103 | tabersonine + NADPH + H+ + O2 |
first step in vindoline boxynthesis |
Catharanthus roseus |
16-hydroxytabersonine + NADP+ + H2O |
- |
? |
| 1.14.14.103 | tabersonine + NADPH + H+ + O2 |
indole alkaloid synthesis |
Catharanthus roseus |
16-hydroxytabersonine + NADP+ + H2O |
- |
? |
